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My academic publications

The following articles were published during my academic career (as S Kettle):

Hutchinson S, Aplin RT, Webb H, Kettle S, Timmermans J, Boers GH, Handford PA. Molecular effects of homocysteine on cbEGF domain structure: insights into the pathogenesis of homocystinuria. J Mol Biol 2005; 346: 833–44.

Kettle S, Cardy CM, Hutchinson S, Sykes B, Handford PA. Characterisation of fibrillin-1 cDNA clones in a human fibroblast cell line that assembles microfibrils. Int J Biochem Cell Biol 2000; 32: 201–14.

Halliday D, Hutchinson S, Kettle S, Firth H, Wordsworth P, Handford PA. Molecular analysis of eight mutations in FBN1. Hum Genet 1999; 105: 587–97.

Kettle S, Yuan X, Grundy G, Knott V, Downing AK, Handford PA. Defective calcium binding to fibrillin-1: consequence of an N2144S change for fibrillin-1 structure and function. J Mol Biol 1999; 285: 1277–87.

Kettle S, Alcami A, Khanna A, Ehret R, Jassoy C, Smith GL. Vaccinia virus serpin B13R (SPI-2) inhibits interleukin-1β-converting enzyme and protects virus-infected cells from TNF- and Fas-mediated apoptosis, but does not prevent IL-1β-induced fever. J Gen Virol 1997; 78: 677–85.

Kettle S, Blake NW, Law KM, Smith GL. Vaccinia virus serpins B13R and B22R do not inhibit antigen presentation to class I-restricted cytotoxic T lymphocytes. J Gen Virol 1995; 76: 2393–8.

Blake NW, Kettle S, Law KM, Gould K, Bastin J, Townsend AR, Smith GL. Vaccinia virus serpins B13R (SPI-2) and B22R (SPI-1) encode Mr 38.5 and 40K, intracellular polypeptides that do not affect virus virulence in a murine intranasal model. Virology 1995; 206: 136–47.

Sharp NJH, Kornegay JN, van Camp SD, Herbstreith MH, Secore SL, Kettle S, Hung WY, Constantinou CD, Dykstra MJ, Roses AD, Bartlett RJ. An error in dystrophin mRNA processing in golden retriever muscular dystrophy, an animal homologue of Duchenne muscular dystrophy. Genomics 1992; 13: 115–21.

Schofield JP, Vaudin M, Kettle S, Jones DS. A rapid semi-automated microtiter plate method for analysis and sequencing by PCR from bacterial stocks. Nucleic Acids Res 1989; 17: 9498.